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Which type of antigen would have the greatest immunogenicity


A) One that is small,simple,familiar,and abundant
B) One that is small but complex and rare
C) One that is large,complex,foreign,and abundant
D) One that is large but simple and familiar

E) C) and D)
F) B) and D)

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Negative selection is the process by which cells learn self-tolerance.

A) True
B) False

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Metals and plastics of artificial implants generally have high immunogenicity.

A) True
B) False

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Protozoans are obligate intracellular parasites.

A) True
B) False

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Upon activation,a T-lymphocyte


A) ceases dividing and becomes a plasma cell.
B) ceases dividing and becomes a memory cytotoxic helper cell.
C) proliferates to form clones and memory cells.
D) proliferates to form B cells and plasma cells.

E) All of the above
F) A) and B)

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B-lymphocytes cannot bind directly with an antigen,and so require presentation by another type of cell.

A) True
B) False

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As T-lymphocytes leave the thymus,they are


A) naive and not yet competent.
B) naive and immunocompetent.
C) activated but not yet competent.
D) activated and immunocompetent.

E) C) and D)
F) B) and D)

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A fever __________ reproduction of bacteria and ___________ CAMs on the endothelium of capillaries of lymph nodes.


A) stimulates;increases
B) stimulates;decreases
C) inhibits;increases
D) inhibits;decreases

E) A) and B)
F) C) and D)

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"Booster" shots are required following certain vaccinations because the memory B-lymphocytes produced in response to the initial vaccination don't survive indefinitely.

A) True
B) False

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The microglia of the brain are macrophages.

A) True
B) False

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"Complement" refers to a group of


A) white blood cells.
B) antibodies.
C) plasma proteins.
D) molecules on the surface of pathogenic microbes.

E) A) and B)
F) All of the above

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Active immunity is a natural process,whereas passive immunity is generated artificially.

A) True
B) False

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Erythrocytes are antigen-presenting cells.

A) True
B) False

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Antigen-presenting cells are ________________,and they display antigens to both ________________ and ______________.


A) immune cells;B-lymphocytes;T-lymphocytes
B) immune cells;helper T-lymphocytes;cytotoxic T-lymphocytes
C) any nucleated cell;B-lymphocytes;T-lymphocytes
D) any anucleate cell;helper T-lymphocytes;cytotoxic T-lymphocytes
E) any blood cell;helper B-lymphocytes;cytotoxic B-lymphocytes

F) A) and D)
G) All of the above

Correct Answer

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Opsonization involves


A) cross-linking several antigens together so that they are no longer soluble,and it is facilitated by the Fc region of the antibody.
B) marking a target for phagocytosis,and it is facilitated by interaction of the Fc region of the antibody with a phagocyte.
C) activation of NK cells,and it is a function of the antigen-binding site of the antibody.
D) fixation of antibodies in the IgG and IgM classes,and it involves the antigen-binding site of the antibody.

E) B) and C)
F) All of the above

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Most bacterial species are pathogenic.

A) True
B) False

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The concentration of a particular antibody within the blood is referred to as the antibody ________.

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MHC class I molecules present peptide fragments that are either "self" or "nonself";in either case,the fragment becomes bound to the molecule while


A) in the Golgi apparatus.
B) in the cytosol.
C) in a secretory vesicle.
D) in the rough endoplasmic reticulum.

E) B) and C)
F) A) and D)

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Helper T-lymphocytes are also known as


A) cytotoxic T-lymphocytes.
B) CD8+cells.
C) CD4+cells.
D) T8 cells.
E) memory T-lymphocytes.

F) A) and C)
G) B) and E)

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Passive immunity lasts


A) from days to weeks,and involves development of memory cells.
B) from days to weeks,and does not involve development of memory cells.
C) from years to a lifetime,and involves the development of memory cells.
D) from years to a lifetime,and does not involve development of memory cells.

E) A) and B)
F) None of the above

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