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In addition to osmoregulation, the kidneys participate in regulating blood pressure. Specialized cells of the efferent arteriole, called the _____ apparatus, secrete the hormone renin in response to a drop in blood pressure. This, in turn, triggers additional responses that help raise blood pressure.

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One of the most extensive animal radiations is that of terrestrial arthropods (including insects) . They excrete uric acid as their form of nitrogenous waste. Why does excreting uric acid allow them to conserve more water than a mammal that has extensive kidney tubules for water reabsorption?


A) The high solubility of uric acid allows the excretory system to reabsorb water.
B) Uric acid levels stay high in the blood, maintaining a strong osmotic gradient, which allows water to be reabsorbed.
C) After precipitation, uric acid no longer exerts osmotic pressure; water returns to the hypertonic tissues.
D) After precipitation, uric acid no longer exerts osmotic pressure; water leaves the hypertonic tissues.

E) A) and B)
F) All of the above

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By the time the filtrate leaves the proximal convoluted tubule, about 75% of the water and most of the electrolytes and solutes have been reabsorbed into the bloodstream.

A) True
B) False

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Osmoconformers tend to live in environments with variable solute concentrations.

A) True
B) False

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Which of the following CORRECTLY describes the path of excretory fluids through a mammalian nephron?


A) glomerulus, Bowman's space, proximal convoluted tubule, loop of Henle, distal convoluted tubule, collecting duct
B) glomerulus, Bowman's space, proximal convoluted tubule, distal convoluted tubule, loop of Henle, collecting duct
C) glomerulus, Bowman's space, loop of Henle, proximal convoluted tubule, distal convoluted tubule, collecting duct
D) Bowman's space, glomerulus, proximal convoluted tubule, distal convoluted tubule, loop of Henle, collecting duct
E) collecting duct, proximal convoluted tubule, loop of Henle, distal convoluted tubule, Bowman's space, glomerulus

F) A) and D)
G) B) and C)

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The blood vessels surrounding the loop of Henle are collectively called the _____ and are arranged in a countercurrent organization, just like the loop of Henle.

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You have just finished a really long workout at the gym. You sweat quite a bit, and now feel thirsty. You have lost a lot of water and some ions while sweating. Decreased Na+ in body fluids (Na+ depletion) _____ renin secretion.


A) increases
B) decreases
C) has no effect on

D) B) and C)
E) All of the above

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What is the significance of the fact that the loop of Henle extends into the medulla of the kidney with sections that run antiparallel to one another?


A) The loop of Henle maintains the concentration gradient in the kidney.
B) The loop of Henle generates the concentration gradient in the kidney.
C) The loop of Henle contains more aquaporins.
D) The loop of Henle is permeable to urea on one side, but not the other.

E) C) and D)
F) A) and B)

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List the three forms of nitrogenous waste in order from the one that requires the most water to eliminate it to the one that requires the least water to eliminate it.


A) uric acid, urea, ammonia
B) uric acid, ammonia, urea
C) urea, uric acid, ammonia
D) ammonia, uric acid, urea
E) ammonia, urea, uric acid

F) B) and C)
G) C) and E)

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You have just finished a really long workout at the gym. You sweat quite a bit, and now feel thirsty. Na+ reabsorption will increase in the distal convoluted tubule.

A) True
B) False

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The loop of Henle in the nephrons of desert-dwelling kangaroo rats is much longer than the loop of Henle in humans. What is the advantage of this increased length for the kangaroo rat?


A) A longer loop of Henle can generate a larger concentration gradient, which allows for the production of a more concentrated urine.
B) A longer loop of Henle can generate a smaller concentration gradient, which allows for the production of a more concentrated urine.
C) A longer loop of Henle can generate a larger concentration gradient, which allows for the production of a less concentrated urine.
D) A longer loop of Henle can generate a smaller concentration gradient, which allows for the production of a less concentrated urine.
E) None of the answer options is correct.

F) A) and D)
G) A) and B)

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Placing a freshwater flatworm like Planaria in a dilute salt solution results in:


A) more dilute urine.
B) more concentrated urine.
C) no change in urine concentration.

D) B) and C)
E) A) and C)

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Multicellular animals with pressurized circulatory systems use a three-step process to isolate and eliminate wastes. Arrange these steps in order from earliest to latest.


A) filtration, reabsorption, secretion
B) secretion, filtration, reabsorption
C) filtration, secretion, reabsorption
D) reabsorption; filtration, secretion
E) secretion, reabsorption, filtration

F) B) and C)
G) All of the above

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Desert reptiles excrete nitrogenous waste in the form of uric acid, which allows them to reabsorb most of the water from their urine.

A) True
B) False

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Which of the following statements about the control of blood volume and blood pressure is NOT true?


A) Angiotensin II stimulates the release of antidiuretic hormone, which increases salt and water uptake by the distal convoluted tubule.
B) A drop in blood pressure stimulates the cells of the juxtaglomerular apparatus to release renin.
C) Inactive angiotensinogen is converted to angiotensin II by an enzyme released from the lungs.
D) Angiotensin II causes the smooth muscle in the walls of the arterioles to contract.
E) None of the answer options is false.

F) B) and D)
G) A) and B)

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Which of the following statements about nitrogenous waste excretion is CORRECT?


A) Uric acid is less toxic than ammonia, but more energetically costly to produce.
B) Ammonia is more toxic than urea, but requires less water for excretion.
C) Urea is less toxic than uric acid, but more energetically costly to produce.
D) Uric acid is less toxic than urea, but requires more water for excretion.
E) Ammonia is less toxic than uric acid, but requires more water for excretion.

F) A) and B)
G) A) and C)

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Which of the following statements about excretory organs in complex multicellular animals is NOT true?


A) All of the materials that are removed from the blood during filtration will eventually be excreted.
B) Excretory systems are important for balancing both electrolyte and water levels in the body.
C) If organisms relied on molecule-specific active transport of wastes alone, then novel toxic compounds could not be excreted.
D) The process of excretion has more steps in complex multicellular animals with pressurized circulatory systems than in simple multicellular animals.
E) None of the answer options is false.

F) C) and D)
G) A) and E)

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The loops of Henle create a concentration gradient in the interstitial fluid surrounding the loop, with the concentration highest in the _____ and lowest in the _____ of the kidney.


A) inner medulla; cortex
B) outer medulla; inner medulla
C) outer medulla; cortex
D) cortex; inner medulla
E) cortex; outer medulla

F) B) and E)
G) A) and E)

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Osmoregulators have _____ internal solute concentrations compared to their external environment.


A) the same
B) different
C) always lower
D) always higher

E) B) and D)
F) C) and D)

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Which of the following statements about the distal convoluted tubule is NOT true?


A) The filtrate entering the tubule is hypertonic relative to the interstitial space.
B) Urea is the principal solute found within the filtrate in the distal convoluted tubule.
C) Other wastes from the bloodstream are actively secreted into the distal convoluted tubule.
D) The distal convoluted tubule delivers filtrate to the collecting duct.
E) None of the other answer options is false.

F) D) and E)
G) None of the above

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